Contributory factors to anaemia in pregnancy in Benin City, Nigeria

Main Article Content

O Akinola
M Nwagu
N Uwaibi
H Egbo
G Omokhua
V Ohenhen
J Erhabor
E Omozua
O Adeyemi

Abstract

Introduction: About a third of the world population is affected by anaemia, with most of this burden on developing countries, Nigeria inclusive. Anaemia, though preventable, is a major contributor to maternal morbidity and mortality. Factors associated with anaemia in pregnancy include poor nutrition, socio-cultural behaviours and certain infections. Methods: We studied the habits, dietary diversity and pattern of infections that may explain occurrence of anaemia in 386 pregnant women (18-45years old) attending antenatal care at the Stella Obasanjo Women and Children Hospital (SOWCH) and the Central Hospital in Benin City, Nigeria between July-December, 2019. Data obtained was analyzed using SPSS version 26.0 and level of significance (p) set at ≤0.05. Results: The mean age (±SD) of the study population was 30±4years, 20 (5.2%) women had positive MP, 11 (2.8%) were HIV positive, 3 (0.8%) were HBsAg positive while none was found with a reactive anti-HCV. The mean Hb (±SD) was 10.9± 1.1g/dl. The prevalence of anaemia was 45.6% with only mild and moderate forms recorded. Factors associated with anaemia were lack of ITN use (p= 0.03), alcohol consumption during pregnancy (p= 0.00) and HIV infection (p=0.01). There was a significant correlation between Hb and gestational age (p=0.00) as well as duration of last child birth (p= 0.02). The mean WDDS (±SD) was 9±1, with 99.0% participants having a high WDDS. There was no association between WDDS and occurrence of anaemia. Conclusion: the high burden of anaemia persists. Health promotion strategies to limit factors associated with anaemia in pregnancy are advocated. The role of dietary diversity on anemia remains inconclusive. Key words: Anaemia, Dietary diversity, alcohol in pregnancy, HIV infection, malaria

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1.
Akinola O, Nwagu M, Uwaibi N, Egbo H, Omokhua G, Ohenhen V, Erhabor J, Omozua E, Adeyemi O. Contributory factors to anaemia in pregnancy in Benin City, Nigeria . Wes J Med Biomed Sci [Internet]. 2022 Feb. 13 [cited 2024 May 16];3(1):69-7. Available from: https://wjmbs.com.ng/index.php/wjmbs/article/view/63
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References

de Benoist B, McLean E, Egli I, Cogswell M. Worldwide Prevalence of Anaemia 19932005: WHO Global Database on Anaemia. WHO, Geneva, Switzerland. 2008.

World Health Organization (WHO). Anaemia. Available at www.who.int (Accessed 12/03/2019)

Sanghvi TG, Harvey PW, Wainwright E. Maternal iron-folic acid supplementation programs: evidence of impact and implementation. Food Nutr. Bull. 2010; 31: 100107.

Allen LH. Pregnancy and iron deficiency: unresolved issues. Nutr Rev 1997; 55: 91-101.

Harvey T, Zkik A, Auges M, Clavel T. Assessment of iron deficiency and anaemia in pregnant women: an observational French study. Womens Health. 2016; 12: 95102.

Davas I, Marangoz D, Varolan A, Akyol A, Baksu B. Gebelikte değişik seviyelerdeki anemilerde demir alınımının maternal, doğum ve perinatal sonuçlara etkileri. J Turk Soc Obstet Gynecol 2008; 5: 174-81.

Suryanarayana R, Santhuram AN, Chandrappa M, Shivajirao P, Rangappa SR. Prevalence of anaemia among pregnant women in rural population of Kolar district. Int J Med Sci Pub Health. 2016; 5: 454-458.

Kordorwu HEM. Factors associated with anaemia in pregnancy among antenatal care attendants in keta municipality. A dissertation submitted to University of Ghana. 2018; 1-80.

Nduka FO, Egbu A, Okafor C, Nwaugo VO. Prevalence of malaria parasites and anaemia in pregnant and non-pregnant women in Aba and Okigwe towns of southeast Nigeria. Animal Res Intl. 2006; 3: 508 512.

Oladeinde BH, Omoregie R, Olley M, Anunibe JA. Prevalence of HIV and Anaemia among pregnant women. North American J Med Sci. 2011; 3: 548-551.

World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Geneva, Switzerland. World Health Organization. 2011. Available at http://www.who.int/vmnis/indicators/haemoglobin.pdf.

Edris M. Nutrition lecture notes for health extension trainees in Ethiopia, Gondar University, in collaboration with the Ethiopia Public Health Training Initiative (EPHTI), the carter center, the Ethiopia Ministry of Health and the Ethiopia Ministry of Education. 2004.

Stephen G, Mgongo M, Hashim TH, Katanga J, Stray-Pedersen B, Msuya E. Anaemia in Pregnancy: Prevalence, Risk Factors, and Adverse Perinatal Outcomes in Northern Tanzania. Hindawi Anaemia.2018; Article ID 1846280, 1-9. Available at https://doi.org/10.1155/2018/1846280.

Amen A, Girmay K. Assessment of Anaemia and Its Associated Factors among Pregnant Women Attending Antenatal Care in Karamara Hospital Jigjiga Town, Eastern Ethiopia. European Journal of Nutr Food Safety. 2015; 5: 699-700.

Obi E, Akunyili DN, Ekpo B, Orisakwe OE: Heavy metal hazards of Nigerian herbal remedies. Sci Total Environ. 2006; 369: 35-41.

Anorlu RI, Oluwole AA, Abudu OO. Sociodemographic factors in anaemia in pregnancy at booking in Lagos, Nigeria. J Obstet Gynaecol. 2006; 26: 773736.

Harrison KA. Anaemia in pregnancy, In; Maternity care in developing countries. J. Carson, KA Harrison, S. Bergston (eds) RCOG press. 2001; 112 128.

Lindsay KL, Gibney ER, McAuliffe FM. Maternal nutrition among women from Sub-Saharan Africa, with a focus on Nigeria, and potential implications for pregnancy outcomes among immigrant populations in developed countries. J Hum Nutr Diet. 2012; 25: 534-546.

Hidru HD, Mengesha MB, Hailesilassie Y, Welay FT. Burden and Determinant of Inadequate Dietary Diversity among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis. Hindawi J Nutr Metab. 2020, Article ID 1272393, 1-10. Available at https://doi.org/10.1155/2020/1272393

Stoltzfus RJ, Luke M, Robert EB. Iron Deficiency Anaemia in Comparative qualification of health risk: Global and Regional Burden of Disease Attributed to Selected Major Risk Factors, edited by Majid Ezzati, Alan D. Lopez, Anthony Rodgers, and Christopher J. L. Murray, 163209. Geneva, Switzerland; World Health Organization. 2004.

Agu PU, Ogboi JS, Akpoigbe K, Okeke T, Ezugwu E. Impact of Plasmodium falciparum and hookworm infections on the frequency of anemia in pregnant women of rural communities in Enugu, South East Nigeria. Pan Afr Med J. 2013; 14: 27.

Kumar P, Pore P, Patil U. Maternal anaemia and its impact on perinatal outcome in a tertiary care hospital of Pune, in Maharashtra. Indian J Basic Appl Med Res. 2012; 1: 111-119.

McLean, E, Cogswell M, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO, vitamin and mineral nutrition information system. 1993-2005. Public health nutr. 2009; 12: 444-454.

Nigerian National Minimum wage amended Act (2011). Available at www.ilo.org>docs

FAO and FHI, Minimum Dietary Diversity for Women: A Guide for Measurement, FAO, Rome, Italy, 2016.

Olukosi A, Afolabi BM. Malaria and anaemia among pregnant women living in communities along the coast of Lagos Lagoon, South-west Nigeria. Int J Pregn & Chi Birth. 2018;4: 175‒182.

World Health Organization. A Strategic Framework for Malaria Prevention and Control During Pregnancy in the African Region. AFR/MAL/04/01. Brazzaville: WHO Regional Office for Africa; 2004.

Federal Ministry of Health. National Antimalarial Treatment Guideline. Abuja: FMOH; 2005

Centers for Disease Control and Prevention. Foetal Alcohol Spectrum Disorders. Available at www.cdc.gov v/ncbddd/fasd/alcohol-use.html

Kehinde OS, Adegoke AE. Taking alcohol by deception: an analysis of ethanol concentration of “paraga” an alcoholic herbal mixture in Nigeria. BMC Res Notes. 2012; 5:127. Available at http://www.biomedcentral.com/1756-0500/5/127

Onwuka CI, Ugwu EO, Dim CC, Menuba IE, Iloghalu EI, Onwuka CI. Prevalence and Predictors of Alcohol Consumption during Pregnancy in South-Eastern Nigeria. J Clin Diagn Res. 2016; 10: 10-13.

Ordinioha B, Brisibe S. Alcohol consumption among pregnant women attending the ante-natal clinic of a tertiary hospital in South-South Nigeria. Niger J Clin Pract. 2015; 18: 13-17.

Sholeye OO, Badejo CA, Jeminusi OA. Dietary habits of pregnant women in Ogun-East Senatorial Zone, Ogun State, Nigeria: A comparative study. Int J Nutr Metabolism. 2014; 6: 42-49. DOI: 10.5897/IJNAM2014.0170

Kever RT, Martins SD, Lola N, Dathini H, Habu H, Fatima AA, et al. Knowledge and attitude of pregnant Women towards dietary practices in Yerwa Clinic, Maiduguri Metropolitan Council; Borno State Nigeria. J Res Nurs Midwifery. 2015; 4: 1219. Available at https://doi. org/10.14303/jrnm.2014.027.

Ehwarieme AT, Amiegheme EF, Enosekhafoh B. Knowledge and practice of healthy nutrition among pregnant women attending antenatal clinic at selected private hospitals in Benin City. Int J Nursing and Midwifery. 2019; 11: 75-86. DOI: 10.5897/IJNM2019.0379.

Ali F, Thaver I, Khan SA. Assessment of dietary diversity and nutritional status of pregnant women in Islamabad, Pakistan. J Ayub Med Coll Abbottabad. 2014; 26: 506509.

McDonald CM, McLean J, Kroeun H, Talukder A, Lynd LD, Green TJ. Household food insecurity and dietary diversity as correlates of maternal and child undernutrition in rural Cambodia. Euro J Clin Nutr. 2015; 69: 242246.

Oladeinde BH, Omoregie R, Odia I, Oladeinde OB. Prevalence of Malaria and Anaemia among Pregnant Women Attending a Traditional Birth Home in Benin City, Nigeria. Oman Med J. 2012; 27: 232-236. DOI 10. 5001/omj.2012.52

Mathison BA, Pritt BS. Update on malaria diagnostics and test utilization. J Clin Microbiol. 2017; 55: 2009 2017. https://doi.org/ 10.1128/JCM.02562-16.

Ikeako LC, Ezegwui HU, Ajah LO, Dim CC, Okeke TC. Seroprevalence of Human Immunodeficiency Virus, Hepatitis B, Hepatitis C, Syphilis, and Co-infections among Antenatal Women in a Tertiary Institution in South East, Nigeria. Ann Med Health Sci Res. 2014; 4: 954958. DOI: 10.4103/2141-9248.144925.

Saaka M, Oladele J, Larbi A, Hoeschle-Zeledon I. Dietary Diversity Is Not Associated with Haematological Status of Pregnant Women Resident in Rural Areas of Northern Ghana. Hindawi J Nutr Metab. 2017; Article ID 8497892, 1-10. Available at https://doi.org/10.1155/2017/8497892.

Grum T, Brhane E, Hintsa S, Kahsay G. Magnitude and factors associated with anemia among pregnant women attending antenatal care in public health centers in central zone of Tigray region, northern Ethiopia: a cross sectional study. BMC Pregnancy Childbirth. 2018; 18: 433. Available at https://doi.org/10.1186/s12884-018-2063-z.

Report of a WHO Technical Consultation on Birth Spacing. World Health Organization, 2006. Available at www.who.int.

Bothwell TH. Iron requirements in pregnancy and strategies to meet them. Am J Clin Nutr. 2000; 72: 257S- 264S.

Sholeye OJ, Animashaun VJ, Shorunmu TO. Anaemia in pregnancy and its associated factors among primary care clients in Sagamu, Southwest, Nigeria: A facility-based study. J Family Med Prim Care. 2017; 6: 323329.

Okeudo C, Ezem BU, Ojiyi EC, Anolue FC, Dike EI. Prevalence of anaemia among Human Immune-Deficiency virus (HIV) positive pregnant women at booking in Orlu, in South-Eastern Nigeria. Afr Med J. 2014; 5(1): 4549.

Tunkyia K, Moodley J. Anaemia in pregnancy in a setting of high HIV prevalence rates Kay. South Afr Inf Dis. 2017; 32: 138141.

Zerfu TA, Umeta M, Baye K. Dietary diversity during pregnancy is associated with reduced risk of maternal anemia, preterm delivery, and low birth weight in a prospective cohort study in rural Ethiopia. Am J Clin Nutr. 2016; 103: 14821488.